Brittany Karas, Leonor Côrte-Real, Andreia Valente, Keith R. Cooper, Brian T. Buckley, “Novel screening of transition metal-based anticancer compounds using zebrafish embryo larval assay and ICPMS analysis”. J. Appl. Toxicology. 2019, 39, 1173-1180. doi:https://doi.org/10.1002/jat.3802
Lurdes Gano, Teresa Pinheiro, António P. Matos, Francisco Tortosa, Tiago F. Jorge, M. S. Gonçalves, M. Martins, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, M. Helena Garcia, Fernanda Marques, “Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools”. Anticancer Agents Med Chem. 2019 Mar 18. doi: 10.2174/1871520619666190318152726.
Tiago Moreira, Rita Franciscoa, Elisabeta Comsa, Sophie Duban-Deweer, Valérie Labas, Ana-Paula Teixeira-Gomes, Lucie Combes-Soia, Fernanda Marques, António Matos, Audrey Favrelle, Cyril Rousseau, Philippe Zinck, Pierre Falson, M. Helena Garcia, Ana Preto, Andreia Valente*, “Polymer “ruthenium-cyclopentadienyl” conjugates - new emerging anti-cancer drugs”. Eur. J. Med. Chem. 2019, 168, 373-384. Doi: https://doi.org/10.1016/j.ejmech.2019.02.061
Adhan Pilon, Julia Lorenzo, Sergi Rodriguez-Calado, Pedro Adão, Ana M. Martins, Andreia Valente*, Luis G. Alves*, “New Cyclams and their Copper(II) and Iron(III) Complexes: Synthesis and Potential Application as Anticancer Agents”, ChemMedChem, 2019. Doi: 10.1002/cmdc.201800702
Leonor Côrte-Real, Brittany Karas, Patrícia Gírio, Alexis Moreno, Fernando Avecilla, Fernanda Marques, Brian T. Buckley, Keith R. Cooper, Cathleen Doherty, Pierre Falson, M. Helena Garcia*, Andreia Valente*, “Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand”, European Journal of Medicinal Chemistry, 2019, 163, 853-863. DOI: 10.1016/j.ejmech.2018.12.022
Leonor Côrte-Real, Ricardo G. Teixeira, Patrícia Gírio, Elisabeta Comsa, Alexis Moreno, Rachad Nasr, Hélène Baubichon-Cortay, Fernando Avecilla, Fernanda Marques, M. Paula Robalo, Paulo Mendes, João P. Prates Ramalho, M. Helena Garcia, Pierre Falson*, Andreia Valente*, “Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential”. Inorganic Chemistry, 2018, 57, 4629–4639. doi: 10.1021/acs.inorgchem.8b00358
Ricardo G. Teixeira, Anabela Sanches, Leonor Côrte-Real, Rajendhraprasad Tatikonda, Ana Rita Brás, M. Paula Robalo, Fernando Avecilla, M. Helena Garcia, Ana Preto, Matti Haukka, Andreia Valente*, “Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells”. European Journal of Medicinal Chemistry, 143, 2018, 503-514. DOI: https://doi.org/10.1016/j.ejmech.2017.11.059
António Matos, Filipa Mendes, Andreia Valente, Tânia Morais, Ana Isabel Tomaz, Philippe Zinck, Maria Helena Garcia, Manuel Bicho, Fernanda Marques*, “Ruthenium-based anticancer compounds: insights into their cellular targeting and mechanism of action”. Wiley-VCH book “Ruthenium Complexes – Photochemical and Biomedical Applications” (Editors: Alvin A. Holder, Jimmie L. Bullock Jr., Marc A. Lawrence, Wesley R. Browne, Lothar Lilge), 2018, ISBN: 978-3-527-33957-0.
Adhan Pilon, Patrícia Gírio, Guilherme Nogueira, Fernando Avecilla, Harry Adams, Julia Lorenzo, M. Helena Garcia*, Andreia Valente*, “New iron cyclopentadienyl complexes bearing different phosphane co-ligands: structural factors vs. cytotoxicity”, Journal of Organometallic Chemistry, 852, 2017, 34-42. DOI: 10.1016/j.jorganchem.2017.10.004
Nuno Mendes, Francisco Tortosa, Andreia Valente, Fernanda Marques, António Matos, Tânia S. Morais, Ana Isabel Tomaz, Fátima Gärtner, M. Helena Garcia, “In vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model”, Anti-cancer Agents in Medicinal Chemistry Vol. 17, No. 1, 126-136, 2017. doi: 10.2174/1871520616666160922165133
Guilherme Nogueira, Orsolya Dömötör, Adhan Pilon, M. Paula Robalo, Fernando Avecilla, M. Helena Garcia, Éva A. Enyedy*, Andreia Valente*, “η6-(2-Phenoxyethanol) ruthenium(II)-complexes of 2,2’-bipyridine and its derivatives: solution speciation and kinetic behaviour”, J. Organomet. Chem. 2016, 820, 20-29. doi: 10.1016/j.jorganchem.2016.07.017
Guilherme Nogueira, Audrey Favrelle, Marc Bria, João P. Prates Ramalho, Paulo J. Mendes, Andreia Valente, Philippe Zinck*, “Adenine as organoinitiator for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide”, React. Chem. Eng., 2016, DOI: 10.1039/C6RE00061D.
Tânia S. Morais, Andreia Valente, A. Isabel Tomaz, Fernanda Marques, M. Helena Garcia*, “Tracking anti-tumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds”, Future Medicinal Chemistry 2016, 8, 527-544. doi: 10.4155/fmc.16.7 – selected as special report for the April issue
Leonor Côrte-Real, Fernanda Marques, M. Paula Robalo, Guilherme Nogueira, Fernando Avecilla, Filipa C. Santos, A. Isabel Tomaz, M. Helena Garcia*, Andreia Valente*, “The significant role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: ranging from non-cytotoxic to highly cytotoxic compounds”, Journal of Inorganic Biochemistry 2015, 150, 148–159. doi: 10.1016/j.jinorgbio.2015.06.015
Fernanda Marques, Leonor Côrte-Real, Filipa Mendes, Joana Coimbra, Tânia Morais, Ana Isabel Tomaz, Andreia Valente, Maria Helena Garcia, Isabel Santos, Manuel Bicho, “Anticancer Activity of Structural Related Ruthenium(II) Cyclopentadienyl complexes”, Journal of Biological Inorganic Chemistry 2014, 19(6):853-67. doi: 10.1007/s00775-014-1120-y
Andreia Valente,* M. Helena Garcia, “Syntheses of macromolecular ruthenium compounds: a new approach to the search of anticancer drugs”, Inorganics 2014, 2, 96-114. doi: 10.3390/inorganics2010096
Andreia Valente, Ana Margarida Santos, Leonor Côrte-Real, M. Paula Robalo, Virtudes Moreno, Mercè Font-Bardia, Teresa Calvet, Julia Lorenzo, M. Helena Garcia, “New iron(II) cyclopentadienyl derivative complexes: synthesis and antitumor activity against human leukemia cancer cells”, Journal of Organometallic Chemistry 2014, 756, 52-60. doi: 10.1016/j.jorganchem.2014.01.027
Tiago J. L. Silva, Paulo J. Mendes, Tânia S. Morais, Andreia Valente, M. Paula Robalo, M. Helena Garcia*, “’RuCp’ a versatile moiety: from NLO to antitumor properties”, RUTHENIUM: SYNTHESIS, PHYSICOCHEMICAL PROPERTIES AND APPLICATIONS, In press, Nova Science Publishers, Inc. (NOVA), USA, 2014. ISBN: 978-1-63321-657-0
Andreia Valente,* Maria Helena Garcia, Fernanda Marques, Yong Miao, Cyril Rousseau, Philippe Zinck, “First polymer “ruthenium-cyclopentadienyl” complex as potential anticancer agent”, Journal of Inorganic Biochemistry 2013, 127, 79-81. doi: 10.1016/j.jinorgbio.2013.07.002
Valente, S. Royer, M. Narendra, T. J. L. Silva, P. J. G. Mendes, M. P. Robalo, M. Abreu, J. Heck, M. H. Garcia*, “Synthesis of new Fe(II) and Ru(II) η5-monocyclopentadienyl compounds showing significant second order NLO properties”, Journal of Organometallic Chemistry, 2013, 736, 42-49. doi: 10.1016/j.jorganchem.2013.02.028
Andreia Valente,* Philippe Zinck, “Polymer-Metal Complexes (PMC) for Cancer Therapy”, Recent Research Developments in Polymer Science, 11 (2012):99-128, published by Transworld Research Network, Trivandrum, India (ISBN: 978-81-7895-538-4)
V. Moreno*, M. Font-Bardia, T. Calvet, J. Lorenzo, F. X. Alvilés, M. H. Garcia, T. S. Morais, A. Valente, M. P. Robalo, “DNA interaction and cytotoxicity of new ruthenium (II) cyclopentadienyl derivative complexes containing heteroaromatic ligands”, J. Inorg. Biochem. 2011, 105, 241-249. doi: 10.1016/j.jinorgbio.2010.10.009
M. H. Garcia*, A. Valente, P. Florindo, T. S. Morais, M. F. M. Piedade, M. T. Duarte, V. Moreno, F. X. Avilés, J. Loreno, “New ruthenium(II) mixed metallocene derived complexes: Synthesis, characterization by X-ray diffraction and evaluation on DNA interaction by atomic force microscopy”, Inorganica Chimica Acta 2010, 363, 3765-3775. doi: 10.1016/j.ica.2010.05.034